This recorded lecture, part of our 2024 Free Webinar Series and sponsored by Optos, features Simon Browning, Mehul Doshi, and Ian Jarvis. They explore techniques for detecting central and peripheral changes, including structural alterations within the retina using color and OCT imaging, as well as functional changes through autofluorescent imaging. The session includes case studies demonstrating various imaging types and how a multimodal approach enhances disease detection and monitoring. Additionally, the lecture covers the advantages of early intervention, proper referral mechanisms, and other management scenarios.